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      Why IonBench LC?


Increase LC/MS Performance:  


It make sense for a Mass Spec user to minimize the void volume between the column and the MS Source. This dead volume can be the cause of the chromatography peak tailing. 

See the spectrogram below : 
The spectrogram C has an optimized void volume (10µL)
The spectrogram G is a standard configuration, void volume of 50 µL



 
Analysis of two couples of isobaric (250 and 264 m/z) substrate and metabolites performed on the Agilent 1290 Infinity UHLPLC / Agilent 6460. ). Mobile phase: ammoniumformate 20 mM pH 9 buffer and acetonitrile. Elution mode: 15%–35% of organic modifier in 3 min at 600  _L/min. Injection volume: 2  µL. Using the same gradient conditions,the separation was carried out using Waters Acquity BEH Shield 1.7  _m, 1.0 mm × 50 mm. Mobile phase flow rate: 135  µL/min. Injection volume: 0.45  µL.
A Dead volume of 50 µL.
B Dead volume of optimized to 10 µL
Source : Dany Spaggiari, Szabolcs Fekete, Philippe J. Eugster, Jean-Luc Veuthey, Laurent Geiser,Serge Rudaz, Davy Guillarme, Journal of Chromatography A, 1310 (2013) 45– 55
 
With IonBench LC, you can optimize the global performance of your LC/MS combination by adjusting the height and see real benefits of the system mobility by placing the column as close as possible to the Mass Spectrometer source.. 



Here is an illustration of a µLC Thermo Ultimate 3000 and Thermo Q Exactive with optimized dead volume installation.


This simple void volume optimization allows you to get the best performance of your LC/MS System. 



Save time:


Do you need to run the same sample on a Triple Quad and on a TOF or Orbitrap for example, in order to get more qualitative results? Currently, after injection on the triple quad, you would need to restart full method on the other LC/MS system [ie change the solvent, the column, wait for the system to be conditioned...] It is, therefore, likely that it will take you one to two hours to perform this.



With IonBench LC on your Triple Quad, if you need to re-inject on another MS technology, just move the LC to the other MS and restart the run in 10 minutes! 

If you want the system still running during the switch, just use a small UPS.
..


IonBench LC: Contributes to Lab Safety & Productivity:


Most operators currently use a step stool to reach the top of the HPLC/UHPLC system. This means that they must obtain the step stool from its storage place, climb up and down to maintain solvents, stand on the small step stool surface area while they are servicing the instrument, and partially block the floor space around the system while they are performing this routine operation. This activity represents multiple opportunities for an accident and takes time. 


With IonBench LC, the operator simply flips a switch to lower the system to a safe and manageable height, performs the solvent task, and raises the platform back up to the required operating height.


Transportable LC:


Another advantage of IonBench LC is its transportable feature. You may have basic HPLC, UHPLC, µLC and nano LC in you lab, as well as Triple quad, Orbitrap, Q Tof with different sensitivity and accuracy.
 


Change your configurations the way you want and get the benefit of multiple configuration, easily !


          




Instruments & lab equipment > table for laboratory microscopy & professional microscopes - Ionbench MS & G3215A Agilent mass spec benches - Breaking news
AB Sciex 4000 Q TRAP
AB Sciex 5000 Q TRAP
AB Sciex 5500 Q TRAP
AB Sciex Q TRAP 4500
AB Sciex Triple Quad 4500
AB Sciex 3200 Q TRAP
AB Sciex 6500 Q TRAP
Agilent 6150
Agilent 6410
Agilent 7200 Q TOF
Agilent ICP-MS 8800
Agilent 7000a
Agilent 5975 (6890N)
Agilent 6490 (5975 LTM-GC/MSD)
Agilent 240 Ion Trap (7890A GC)
Agilent Q-TOF 6550
Agilent 6460 Triple Quad
Agilent 6530 Q-TOF LC/MS
Agilent 7700 ICP/MS
Agilent 7500 ICP/MS
Agilent 7900 ICP/MS
Agilent 6495 LC/MS
Agilent G6520B 6520 Q-TOF
Agilent 6224-6230 LCMS TOF
Agilent 6470 Triple Quad
Agilent 6545 Q-TOF
Agilent 7800 ICP/MS
Agilent 6540 Q-ToF
Agilent 8900 ICP/MS
Analytik Jena PlasmaQuant MS Elite
Bruker Amazon SL
Bruker SCION SQ GC-MS
Bruker SCION TQ GC-MS
Bruker MAXIS IMPACT HD LC/MS
Bruker EVOQ Qube LC-TQ
Bruker EVOQ Elite LC-TQ
Bruker Compact
PerkinElmer Flexar SQ300
PerkinElmer NexION 300 ICP-MS
PerkinElmer CLARUS SQ 8 GC/MS
PerkinElmer NexION 350 ICP-MS
PerkinElmer AxION 2 TOF MS
PerkinElmer NexION 2000 ICP-MS
Shimadzu 2020
Shimadzu 8030
Shimadzu IT-TOF
Shimadzu GC/MS QP2010 SE
Shimadzu GC/MS QP2010 ULTRA
Shimadzu GC/MS TQ8030
Shimadzu 8040 LC/MS
Shimadzu 8080 LC/MS
Shimadzu GCMS-TQ8040
Shimadzu 8050 LC/MS
Shimadzu 8060 LC/MS
Shimadzu 8045 LC/MS
Thermo Exactive
Thermo Q Exactive
Thermo LTQ Velos
Thermo TSQ Quantum Access Max
Thermo TSQ Quantum Ultra
Thermo XSERIES II ICP-MS
Thermo TSQ 8000 GC-MS/MS
Thermo iCAP Q ICP-MS
Thermo TSQ Quantiva MS
Thermo TSQ Endura MS
Thermo Q Exactive GC Orbitrap GC/MS
Thermo TSQ Altis MS
Thermo TSQ Quantis MS
Waters 3100
Waters Acquity SQD
Waters Xevo TQ MS
Waters Xevo TQ-S
Waters Xevo TQD
Waters Xevo G2 TOF
Waters Xevo G2 Q-TOF
Waters Xevo G2-XS QTof
Waters Xevo TQ-S micro
Waters Vion IMS QTof MS 1
Waters TQ XS
Waters Vion IMS QTof MS 2